MON-637 DREADD-Induced POMC(ARC)Neuron Activation Increases Fasting Plasma Glucose Levels Through Changes in Hepatic Gluconeogenic Gene Expression but Not Changes in the HPA Axis Activity

POMC neurons expressed in the ARC are essential for energy balance and glucose homeostasis. It has been suggested the involvement of these neurons in the control of endocrine axes, such as the HPA. During fasting, POMC(ARC) neurons are silenced as an effort to reduce body weight loss and to avoid hy...

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Detalles Bibliográficos
Autores principales: Vieira, Luane da Guia, Fernandes, Alan Carlos, Nascimento, Tais, França, Suzelei de Castro, Antunes-Rodrigues, Jose, Vella, Kristen R, Elias, Lucila, Rorato, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207510/
http://dx.doi.org/10.1210/jendso/bvaa046.1678

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