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SAT-304 Pituitary Stem Cells May Drive Adenomas Causing Cushing’s Disease

Introduction:Cell rests of self-renewing Sox2+ progenitor cells have been identified in the normal pituitary glands(1), however their role in human pituitary tumorigenesis is not understood. Adrenocorticotropic hormone (ACTH) producing microadenomas that cause Cushing’s disease frequently (~70%) lac...

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Detalles Bibliográficos
Autores principales: Asuzu, David, Johnson, Kory, Elkahloun, Abdel, Wu, Weiwei, Nieman, Lynnette, Stratakis, Constantine A, Chittiboina, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207599/
http://dx.doi.org/10.1210/jendso/bvaa046.1292