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SUN-269 Activation of GFRAL Neurons Decreases Food Intake via Aversive Pathways

Growth and differentiation factor 15 (GDF15), an anorexigenic peptide that represents a promising candidate for anti-obesity treatment, acts via GDNF Family Receptor Alpha Like (GFRAL), which is expressed almost exclusively on a subset of neurons in the area postrema (AP). To determine the function...

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Detalles Bibliográficos
Autores principales: Sabatini, Paul, Frikke-Schmidt, Henriette, Rupp, Alan, Gordian, Desiree, Myers Jr, Martin, Seeley, Randy John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207650/
http://dx.doi.org/10.1210/jendso/bvaa046.1272