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SUN-269 Activation of GFRAL Neurons Decreases Food Intake via Aversive Pathways
Growth and differentiation factor 15 (GDF15), an anorexigenic peptide that represents a promising candidate for anti-obesity treatment, acts via GDNF Family Receptor Alpha Like (GFRAL), which is expressed almost exclusively on a subset of neurons in the area postrema (AP). To determine the function...
Autores principales: | Sabatini, Paul, Frikke-Schmidt, Henriette, Rupp, Alan, Gordian, Desiree, Myers Jr, Martin, Seeley, Randy John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207650/ http://dx.doi.org/10.1210/jendso/bvaa046.1272 |
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