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SAT-587 Molecular Markers of Beige Adipose Following ESR1 Knockdown in the Mediobasal Hypothalamus of Adult Female Rhesus Monkeys

Our studies in female marmoset monkeys show that the ablation of ovarian estradiol (E(2)) production fails to alter energy homeostasis or body fat accumulation. Peripheral E(2) may therefore not play a crucial role in metabolic regulation in female primates. shRNA-mediated knockdown of ESR1 expressi...

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Detalles Bibliográficos
Autores principales: Bandaru, Sindhura, Flowers, Matthew T, Perlin, Sona, Willging, Molly M, Greinwald, Emily P, Levine, Jon E, Abbott, David Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207675/
http://dx.doi.org/10.1210/jendso/bvaa046.112