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MON-712 Restoration of Growth and Fertility in Zebrafish (Danio Rerio) Model with PROP1 Knockout Generated by CRISPR/Cas9 Genomic Editing
Introduction: Hypopituitarism is defined as the deficiency of one or more pituitary hormones and can occur due to pathogenic allelic variants in transcription factors involved in pituitary development. PROP1 gene is responsible for progenitor cell migration from the marginal zone to the anterior lob...
Autores principales: | Bissegatto, Débora Delmonte, Fernandes, Bianca Helena Ventura, da Silva, Caroline Caetano, Chen, Wenbiao, Junqueira, Mara de Souza, Carvalho, Luciani Renata Silveira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207714/ http://dx.doi.org/10.1210/jendso/bvaa046.1138 |
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