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OR04-01 MRAP2 Regulates Energy Homeostasis by Promoting Primary Cilia Localization of MC4R
Genetic studies in humans and mice have demonstrated that the Melanocortin 4 Receptor (MC4R) is essential for adequate regulation of food intake and body weight. MC4R is expressed in a small population of hypothalamic neurons and very little is known about its molecular and cellular dynamics in vivo...
Autores principales: | Bernard, Adelaide A, Naharros, Irene Ojeda, Guglielmetti, Florence Bourgain, Yue, Xinyu, Vaisse, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207783/ http://dx.doi.org/10.1210/jendso/bvaa046.1166 |
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