SAT-435 A Direct Comparison of Thyroid Hormone Receptor (THR) Protein Levels in Mice Provides Unexpected Insights into TH Action

Thyroid Hormone (TH) action is mediated by three major THR isoforms α1, β1 and β2 (THRA1, THRB1 and THRB2), encoded by two genes Thra and Thrb. A fourth non-T(3) binding isoform is termed THRA2. Previous characterization and comparison of THR isoform expression using QPCR of mRNA levels does not ass...

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Detalles Bibliográficos
Autores principales: Bansal, Sanya, Minakhina, Svetlana, Zhang, Alice, Brotherton, Michael, Janodia, Rucha, Oliveira, Vanessa De, Tadepalli, Shaan, Wondisford, Fredric Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Thyroid
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207864/
http://dx.doi.org/10.1210/jendso/bvaa046.1904

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