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SUN-260 Dual Role of Carboxypeptidase E in Prohormone Processing and a Novel Neurotrophic Factor Mediating Neuroprotection and Cognitive Functions in Hippocampal CA3 Neurons in Mice

Stress causes release of glucocorticoids from the adrenals which then circulate to the brain. High concentrations glucocorticoid from chronic severe stress results in pathophysiology in the brain, including neuronal degeneration, cell death and cognitive dysfunction, leading to diseases such as Alzh...

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Detalles Bibliográficos
Autores principales: Xiao, Lan, Sharma, Vinay, Toulabi, Leila, Yang, Xuyu, Lee, Cheol, Abebe, Daniel, Peltekian, Areg, Arnaoutova, Irina, Loh, Yoke Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208088/
http://dx.doi.org/10.1210/jendso/bvaa046.100