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MON-199 Targeting Pheochromocytoma/Paraganglioma with Polyamine Inhibitors

Background: Pheochromocytomas (PCCs) and paragangliomas (PGLs) are neuroendocrine tumors that are mostly benign. Metastatic disease occurs in about 10% of cases, and for these patients no effective therapies are available. Patients with mutations in the succinate dehydrogenase subunit B (SDHB) gene...

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Detalles Bibliográficos
Autores principales: Ghayee, Hans Kumar, Rai, Sudhir, Bril, Fernando, Hatch, Heather, Xu, Yiling, Kalavalapalli, Srilaxami, Garrett, Timothy, Plant, Dan, Bose, Prodip, Hromas, Robert, Cusi, Kenneth, Tischler, Arthur, Gupta, Priyanaka, Bibb, James, Beuschlein, Felix, Robledo, Mercedes, Calsina, Bruna, Timmers, Henri, Taieb, David, Kroiss, Matthias, Richter, Susan, Eisenhofer, Graeme, Bergeron, Raymond, Pacak, Karel, Tevosian, Sergei G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208096/
http://dx.doi.org/10.1210/jendso/bvaa046.1165