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SAT-426 Macro-Thyroid Stimulating Hormone (TSH) in Children
Macro-TSH is mainly a complex of TSH with anti-TSH autoantibodies. Due to its large molecular size (>150 kDa), it accumulates in the circulation resulting in elevated serum TSH concentrations. Because the bioactivity of macro-TSH is low, treatment with thyroxine is not necessary. The prevalence o...
Autores principales: | Hattori, Naoki, Matsuda, Takeshi, Chihara, Kazuhisa, Nishioka, Junko, Elmaoğulları, Selin, Shimatsu, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208191/ http://dx.doi.org/10.1210/jendso/bvaa046.725 |
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