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OR16-06 Age-Associated Local GH Promotes Colon Neoplasia
Colon polyp and cancer frequency increase with age, yet little is known about age-related mechanisms underlying development of these neoplasms. Defective DNA damage response and accumulation of unrepaired DNA damage can trigger genomic instability and cellular transformation. Patients with acromegal...
Autores principales: | Chesnokova, Vera M, Zonis, Svetlana, Apostolou, Nasia, Hannah, Estrada Q, Knott, Simon, Wawrowsky, Kolja, Ben-Shlomo, Anat, Barrett, Robert, Gorbunova, Vera, Karalis, Katia, Melmed, Shlomo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208399/ http://dx.doi.org/10.1210/jendso/bvaa046.1474 |
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