SUN-351 Sex Is a Strong Variable in the Mineral Metabolism Defects and Endocrine Dysfunction Associated with the Murine Adenine Diet Model of Chronic Kidney Disease (CKD)

The adenine diet is widely used in animal models to produce a tubulointerstitial fibrosis and inflammation that mimics human CKD in many aspects. These include the biochemical manifestations hyperphosphatemia and anemia, as well as endocrine dysfunction with elevated FGF23 and hyperparathyroidism. M...

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Detalles Bibliográficos
Autores principales: Liesen, Michael P, Noonan, Megan L, Clinkenbeard, Erica, Ni, Pu, Agoro, Rafiou, Tippen, Samantha P, Hum, Julia, White, Kenneth E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Bone and Mineral Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208411/
http://dx.doi.org/10.1210/jendso/bvaa046.658

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