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SAT-LB97 MiRNA-99a and mTOR2 Mediate Enhanced Endothelial Mineralocorticoid Receptor Signaling-Induced Activation of Sodium Channel and Endothelium Stiffness

In diet induced obesity enhanced endothelial cell (EC) mineralocorticoid receptor (MR) (ECMR) and downstream sodium channel (EnNaC) activity increases oxidative stress and inflammation, thereby promoting vascular stiffness and associated impaired endothelial mediated relaxation. For example, consump...

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Detalles Bibliográficos
Autores principales:	Jia, Guanghong, Aroor, Annayya R, Habibi, Javad, Yang, Yan, DeMarco, Vincent G, Hill, Michael A, Whaley-Connell, Adam T, Jaisser, Frederic, Jaffe, Iris Zamir, Sowers, James R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Cardiovascular Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208520/ http://dx.doi.org/10.1210/jendso/bvaa046.1987

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