Cargando…
MON-033 Androgen Increases the Accumulation of Advanced Glycation End Products in Granulosa Cells by Activating ER Stress in PCOS
Polycystic ovarian syndrome (PCOS) is associated with hyperandrogenism. Previously we found that androgen activated endoplasmic reticulum (ER) stress in granulosa cells of antral follicles in PCOS, contributing to ovarian fibrosis (1) and growth arrest of antral follicles (2). In addition, recent st...
Autores principales: | Azhary, Jerilee Mariam Khong, Harada, Miyuki, Takahashi, Nozomi, Hirota, Yasushi, Koga, Kaori, Osuga, Yutaka, Hiraike, Osamu, Kunitomi, Chisato |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209029/ http://dx.doi.org/10.1210/jendso/bvaa046.182 |
Ejemplares similares
-
MON-201 ER Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS
por: Azhary, Jerilee, et al.
Publicado: (2019) -
RF10 | PMON241 Temporal Changes in Phenotype and Gut microbiota in PCOS Mouse Model Induced by Prenatal Androgen Exposure.
por: Kusamoto, Akari, et al.
Publicado: (2022) -
Upregulation of Aryl Hydrocarbon Receptor in Granulosa Cells by Endoplasmic Reticulum Stress Contributes to the PCOS Pathophysiology
por: Kunitomi, Chisato, et al.
Publicado: (2021) -
MON-027 Activation of Endoplasmic Reticulum Stress Mediates Oxidative Stress-Induced Apoptosis of Granulosa Cells in Ovaries Affected by Endometrioma
por: Kunitomi, Chisato, et al.
Publicado: (2020) -
Activation of Endoplasmic Reticulum Stress in Granulosa Cells from Patients with Polycystic Ovary Syndrome Contributes to Ovarian Fibrosis
por: Takahashi, Nozomi, et al.
Publicado: (2017)