OR01-06 Resistance to Thyroid Hormone Beta Is Associated with an Increase in Hepatic Fat Measured by Transient Elastography (Fibroscan(®)) with Controlled Attenuation Parameter (CAP)

Hepatic regulation of lipid metabolism is dependent on thyroid hormone receptors (TRs) with TRβ as the predominantly expressed TR isoform in the liver. Patients with resistance to thyroid hormone (RTH) harboring mutations in the THRB gene have loss-of-function of TRβ. Thus, we investigated whether t...

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Detalles Bibliográficos
Autores principales: Chaves, Carolina Marques, Bruinstroop, Eveline, Refetoff, Samuel, Yen, Paul Michael, Anselmo, Joao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Thyroid
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209135/
http://dx.doi.org/10.1210/jendso/bvaa046.780

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