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Predicting cancer origins with a DNA methylation-based deep neural network model

Cancer origin determination combined with site-specific treatment of metastatic cancer patients is critical to improve patient outcomes. Existing pathology and gene expression-based techniques often have limited performance. In this study, we developed a deep neural network (DNN)-based classifier fo...

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Detalles Bibliográficos
Autores principales: Zheng, Chunlei, Xu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209244/
https://www.ncbi.nlm.nih.gov/pubmed/32384093
http://dx.doi.org/10.1371/journal.pone.0226461