SUN-211 Active Steroid Hormone Synthesis Renders Adrenocortical Cells Highly Susceptible to Type II Ferroptosis Induction

Context: Cell death in the adrenal cortex is ill understood but of high clinical relevance. Resistance of adrenocortical carcinoma (ACC) to current treatment with mitotane and chemotherapy calls for an improved understanding of adrenal cortical cell death processes. Ferroptosis is an iron-dependent...

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Detalles Bibliográficos
Autores principales: Weigand, Isabel, Schreiner, Jochen, Roehrig, Florian, Sun, Na, Laura-Sophie, Landwehr, Urlaub, Hanna, Kiseljak-Vassiliades, Katja, Wierman, Margaret E, Angeli, José Pedro Friedmann, Walch, Axel K, Sbiera, Silviu, Fassnacht, Martin, Kroiss, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209342/
http://dx.doi.org/10.1210/jendso/bvaa046.1931

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