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OR22-01 NF-κB Pathway Is Implicated in Thyroid Embryogenesis

BACKGROUND: Congenital hypothyroidism due to thyroid dysgenesis (CHTD) is the most common congenital endocrine disease with a prevalence of 1:4,000 live births. We have suggested a two-hit hypothesis to explain CHTD, combining an inherited or de novo variant with a post-zygotic event. This model cou...

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Detalles Bibliográficos
Autores principales: Vanier, Stéphanie Larrivée, Magne, Fabien, Jean-Louis, Martineau, Samuels, Mark E, Van Vliet, Guy, Deladoey, Johnny Yvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209357/
http://dx.doi.org/10.1210/jendso/bvaa046.622