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SUN-665 Peripheral CB(1)R Blocker Improves Metabolism in Diet Induced Obese Mice Independent of Hepatic FGF21
Obesity is associated with an overactive endocannabinoid system, and selective blockade of CB(1)R in peripheral tissues, including the liver, reverses HFD-induced metabolic abnormalities by restoring normal lipid and glucose homeostasis. Fibroblast growth factor-21 (FGF21) has emerged as a major end...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209388/ http://dx.doi.org/10.1210/jendso/bvaa046.648 |