OR07-04 A Novel Ex Vivo Live-Cell Interrogative Assay of Human Parathyroid Tissue Reveals Distinct Mechanisms of Calcium Sensing Failure in Primary, Secondary, and Tertiary Hyperparathyroidism

Disruption of calcium homeostasis is common to all forms of hyperparathyroidism (HPT), but the underlying biochemical mechanisms that distinguish the various forms of HPT pathology remain poorly characterized. We previously have observed that the kinetics and amplitude of CASR-mediated signaling var...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Zhang, Run, Foft, Jessica, Starks, Catherine, Gosnell, Jessica Erin, Roman, Sanziana, Sosa, Julie Ann, Koh, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Bone and Mineral Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209402/
http://dx.doi.org/10.1210/jendso/bvaa046.526

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