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OR28-04 Identification of Novel and Rare Receptor Tyrosine Kinase Fusions in Thyroid Fine Needle Aspirates
Introduction: Receptor tyrosine kinases (RTKs) initiate signaling cascades, including growth and differentiation. Activation can occur through chromosomal rearrangements that lead to gene fusions. RTK fusions are potential targets for small molecule inhibitors to treat advanced cancers. The original...
Autores principales: | Wirth, Lori J, Grubbs, Elizabeth G, Livhits, Masha J, Sherman, Steven I, Weitzman, Steven P, Dosiou, Chrysoula, Ladenson, Paul W, Hao, Yangyang, Babiarz, Joshua E, Kennedy, Giulia C, Kloos, Richard T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209442/ http://dx.doi.org/10.1210/jendso/bvaa046.2185 |
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