SAT-303 3D Mapping of the Human Growth Hormone Locus Identifies Putative Regulatory Hubs for Genes Involved in Cellular Signalling and Cancer-Related Pathways

Growth hormone (GH) is a peptide hormone predominantly produced in the pituitary that is crucial for normal growth and metabolism. Downstream effects of GH are mediated through binding to the GH receptor (GHR) and consequent activation of key signalling cascades including JAK-STAT, MAPK, PI3K-Akt an...

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Detalles Bibliográficos
Autores principales: Jain, Lekha, Fadason, Tayaza, Schierding, William, Vickers, Mark Hedley, O’Sullivan, Justin M, Perry, Jo Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209482/
http://dx.doi.org/10.1210/jendso/bvaa046.344

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