MON-LB57 Impact of Imputation Method and Response Cutoffs on Results From the Phase 3 OPTIMAL Study of Oral Octreotide Capsules in Adult Patients With Acromegaly

Objective: The phase 3 CHIASMA OPTIMAL study assessed efficacy and safety of oral octreotide capsules (OOC) in patients with acromegaly controlled on injectable somatostatin receptor ligands (SRLs). Sensitivity analyses were conducted for efficacy endpoints using two methods of imputation (i.e., the...

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Detalles Bibliográficos
Autores principales: Samson, Susan Leanne, Nachtigall, Lisa B, Fleseriu, Maria, Gordon, Murray B, Jensterle, Mojca, Elenkova, Atanaska, Ludlam, William Henry, Patou, Gary, Haviv, Asi, Biermasz, Nienke, Trainer, Peter James, Strasburger, Christian Joseph, Kennedy, Laurence, Melmed, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209634/
http://dx.doi.org/10.1210/jendso/bvaa046.2120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209634/
http://dx.doi.org/10.1210/jendso/bvaa046.2120

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