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Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay
Action potential generation (spiking) in the neocortex is organized into repeating non-random patterns during both awake experiential states and non-engaged states ranging from inattention to sleep to anaesthesia—and even occur in slice preparations. Repeating patterns in a given population of neuro...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209911/ https://www.ncbi.nlm.nih.gov/pubmed/32248782 http://dx.doi.org/10.1098/rstb.2019.0233 |
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author | Liu, Tang-Yu Watson, Brendon O. |
author_facet | Liu, Tang-Yu Watson, Brendon O. |
author_sort | Liu, Tang-Yu |
collection | PubMed |
description | Action potential generation (spiking) in the neocortex is organized into repeating non-random patterns during both awake experiential states and non-engaged states ranging from inattention to sleep to anaesthesia—and even occur in slice preparations. Repeating patterns in a given population of neurons between states may imply a common means by which cortical networks can be engaged despite brain state changes, but super-imposed on this common firing is a variability that is both specific to ongoing inputs and can be re-shaped by experience. This similarity with specifically induced variance may allow for a range of processes including perception, memory consolidation and network homeostasis. Here, we review how patterned activity in neocortical populations has been studied and what it may imply for a cortex that must be both static and plastic. This article is part of the Theo Murphy meeting issue ‘Memory reactivation: replaying events past, present and future’. |
format | Online Article Text |
id | pubmed-7209911 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-72099112020-05-14 Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay Liu, Tang-Yu Watson, Brendon O. Philos Trans R Soc Lond B Biol Sci Articles Action potential generation (spiking) in the neocortex is organized into repeating non-random patterns during both awake experiential states and non-engaged states ranging from inattention to sleep to anaesthesia—and even occur in slice preparations. Repeating patterns in a given population of neurons between states may imply a common means by which cortical networks can be engaged despite brain state changes, but super-imposed on this common firing is a variability that is both specific to ongoing inputs and can be re-shaped by experience. This similarity with specifically induced variance may allow for a range of processes including perception, memory consolidation and network homeostasis. Here, we review how patterned activity in neocortical populations has been studied and what it may imply for a cortex that must be both static and plastic. This article is part of the Theo Murphy meeting issue ‘Memory reactivation: replaying events past, present and future’. The Royal Society 2020-05-25 2020-04-06 /pmc/articles/PMC7209911/ /pubmed/32248782 http://dx.doi.org/10.1098/rstb.2019.0233 Text en © 2020 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Articles Liu, Tang-Yu Watson, Brendon O. Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay |
title | Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay |
title_full | Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay |
title_fullStr | Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay |
title_full_unstemmed | Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay |
title_short | Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay |
title_sort | patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209911/ https://www.ncbi.nlm.nih.gov/pubmed/32248782 http://dx.doi.org/10.1098/rstb.2019.0233 |
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