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Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay

Action potential generation (spiking) in the neocortex is organized into repeating non-random patterns during both awake experiential states and non-engaged states ranging from inattention to sleep to anaesthesia—and even occur in slice preparations. Repeating patterns in a given population of neuro...

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Detalles Bibliográficos
Autores principales: Liu, Tang-Yu, Watson, Brendon O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209911/
https://www.ncbi.nlm.nih.gov/pubmed/32248782
http://dx.doi.org/10.1098/rstb.2019.0233
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author Liu, Tang-Yu
Watson, Brendon O.
author_facet Liu, Tang-Yu
Watson, Brendon O.
author_sort Liu, Tang-Yu
collection PubMed
description Action potential generation (spiking) in the neocortex is organized into repeating non-random patterns during both awake experiential states and non-engaged states ranging from inattention to sleep to anaesthesia—and even occur in slice preparations. Repeating patterns in a given population of neurons between states may imply a common means by which cortical networks can be engaged despite brain state changes, but super-imposed on this common firing is a variability that is both specific to ongoing inputs and can be re-shaped by experience. This similarity with specifically induced variance may allow for a range of processes including perception, memory consolidation and network homeostasis. Here, we review how patterned activity in neocortical populations has been studied and what it may imply for a cortex that must be both static and plastic. This article is part of the Theo Murphy meeting issue ‘Memory reactivation: replaying events past, present and future’.
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spelling pubmed-72099112020-05-14 Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay Liu, Tang-Yu Watson, Brendon O. Philos Trans R Soc Lond B Biol Sci Articles Action potential generation (spiking) in the neocortex is organized into repeating non-random patterns during both awake experiential states and non-engaged states ranging from inattention to sleep to anaesthesia—and even occur in slice preparations. Repeating patterns in a given population of neurons between states may imply a common means by which cortical networks can be engaged despite brain state changes, but super-imposed on this common firing is a variability that is both specific to ongoing inputs and can be re-shaped by experience. This similarity with specifically induced variance may allow for a range of processes including perception, memory consolidation and network homeostasis. Here, we review how patterned activity in neocortical populations has been studied and what it may imply for a cortex that must be both static and plastic. This article is part of the Theo Murphy meeting issue ‘Memory reactivation: replaying events past, present and future’. The Royal Society 2020-05-25 2020-04-06 /pmc/articles/PMC7209911/ /pubmed/32248782 http://dx.doi.org/10.1098/rstb.2019.0233 Text en © 2020 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Articles
Liu, Tang-Yu
Watson, Brendon O.
Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay
title Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay
title_full Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay
title_fullStr Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay
title_full_unstemmed Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay
title_short Patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay
title_sort patterned activation of action potential patterns during offline states in the neocortex: replay and non-replay
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209911/
https://www.ncbi.nlm.nih.gov/pubmed/32248782
http://dx.doi.org/10.1098/rstb.2019.0233
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