Gene therapy for follistatin mitigates systemic metabolic inflammation and post-traumatic arthritis in high-fat diet–induced obesity

Obesity-associated inflammation and loss of muscle function play critical roles in the development of osteoarthritis (OA); thus, therapies that target muscle tissue may provide novel approaches to restoring metabolic and biomechanical dysfunction associated with obesity. Follistatin (FST), a protein...

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Detalles Bibliográficos
Autores principales: Tang, Ruhang, Harasymowicz, Natalia S., Wu, Chia-Lung, Collins, Kelsey H., Choi, Yun-Rak, Oswald, Sara J., Guilak, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209997/
https://www.ncbi.nlm.nih.gov/pubmed/32426485
http://dx.doi.org/10.1126/sciadv.aaz7492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209997/
https://www.ncbi.nlm.nih.gov/pubmed/32426485
http://dx.doi.org/10.1126/sciadv.aaz7492

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