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FEZF1-AS1在非小细胞肺癌中的研究进展
Nowadays, accumulating evidence indicates that long non-coding RNA (lncRNA) play vital roles in tumorigenesis. As a newly discovered lncRNA, FEZ family zinc finger 1-antisense RNA 1 (FEZF1-AS1) is markedly upregulated in various malignant tumors including non-small cell lung cancer (NSCLC). Aberrant...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
中国肺癌杂志编辑部
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210085/ https://www.ncbi.nlm.nih.gov/pubmed/32228826 http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.05 |
| _version_ | 1783531206267109376 |
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| collection | PubMed |
| description | Nowadays, accumulating evidence indicates that long non-coding RNA (lncRNA) play vital roles in tumorigenesis. As a newly discovered lncRNA, FEZ family zinc finger 1-antisense RNA 1 (FEZF1-AS1) is markedly upregulated in various malignant tumors including non-small cell lung cancer (NSCLC). Aberrant expression of FEZF1-AS1 is related to clinical characteristics of patients with NSCLC and suggests poor prognosis. Moreover, FEZF1-AS1 can regulate numerous biological processes, such as cell proliferation, migration and invasion through different mechanisms. In this article, we systematically summarize the recent research progress of FEZF1-AS1 in NSCLC, which might be a novel target for clinical therapy. |
| format | Online Article Text |
| id | pubmed-7210085 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | 中国肺癌杂志编辑部 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-72100852020-05-14 FEZF1-AS1在非小细胞肺癌中的研究进展 Zhongguo Fei Ai Za Zhi 综述 Nowadays, accumulating evidence indicates that long non-coding RNA (lncRNA) play vital roles in tumorigenesis. As a newly discovered lncRNA, FEZ family zinc finger 1-antisense RNA 1 (FEZF1-AS1) is markedly upregulated in various malignant tumors including non-small cell lung cancer (NSCLC). Aberrant expression of FEZF1-AS1 is related to clinical characteristics of patients with NSCLC and suggests poor prognosis. Moreover, FEZF1-AS1 can regulate numerous biological processes, such as cell proliferation, migration and invasion through different mechanisms. In this article, we systematically summarize the recent research progress of FEZF1-AS1 in NSCLC, which might be a novel target for clinical therapy. 中国肺癌杂志编辑部 2020-04-20 /pmc/articles/PMC7210085/ /pubmed/32228826 http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.05 Text en 版权所有©《中国肺癌杂志》编辑部2020 This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/. |
| spellingShingle | 综述 FEZF1-AS1在非小细胞肺癌中的研究进展 |
| title | FEZF1-AS1在非小细胞肺癌中的研究进展 |
| title_full | FEZF1-AS1在非小细胞肺癌中的研究进展 |
| title_fullStr | FEZF1-AS1在非小细胞肺癌中的研究进展 |
| title_full_unstemmed | FEZF1-AS1在非小细胞肺癌中的研究进展 |
| title_short | FEZF1-AS1在非小细胞肺癌中的研究进展 |
| title_sort | fezf1-as1在非小细胞肺癌中的研究进展 |
| topic | 综述 |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210085/ https://www.ncbi.nlm.nih.gov/pubmed/32228826 http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.05 |
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