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Reduction of FoxP3(+) Tregs by an immunosuppressive protocol of rapamycin plus Thymalfasin and Huaier extract predicts positive survival benefits in a rat model of hepatocellular carcinoma

BACKGROUND: Investigate immunoregulation and anti-tumor immunity of FoxP3(+)Tregs after treatment with rapamycin (RAPA/SRL) plus thymalfasin (Zadaxin) and Huaier extract (PS-T) in a hepatocellular carcinoma (HCC) rat model simulating HCC relapse after liver transplant (LT). METHODS: We successfully...

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Detalles Bibliográficos
Autores principales: Zhou, Lin, Pan, Li-Chao, Zheng, Yong-Gen, Zhang, Xin-Xue, Liu, Zhi-Jia, Meng, Xuan, Shi, Hai-Da, Du, Guo-Sheng, He, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210174/
https://www.ncbi.nlm.nih.gov/pubmed/32395516
http://dx.doi.org/10.21037/atm.2020.03.129