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Reduction of FoxP3(+) Tregs by an immunosuppressive protocol of rapamycin plus Thymalfasin and Huaier extract predicts positive survival benefits in a rat model of hepatocellular carcinoma
BACKGROUND: Investigate immunoregulation and anti-tumor immunity of FoxP3(+)Tregs after treatment with rapamycin (RAPA/SRL) plus thymalfasin (Zadaxin) and Huaier extract (PS-T) in a hepatocellular carcinoma (HCC) rat model simulating HCC relapse after liver transplant (LT). METHODS: We successfully...
Autores principales: | Zhou, Lin, Pan, Li-Chao, Zheng, Yong-Gen, Zhang, Xin-Xue, Liu, Zhi-Jia, Meng, Xuan, Shi, Hai-Da, Du, Guo-Sheng, He, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210174/ https://www.ncbi.nlm.nih.gov/pubmed/32395516 http://dx.doi.org/10.21037/atm.2020.03.129 |
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