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Fast, facile synthesis method for BAL-mediated PVP-bismuth nanoparticles
Bismuth is a water-insoluble non-toxic metallic element used in a wide array of pharmaceutical products, cosmetics, and catalysts, among others. Yet, the research regarding the use of bismuth nanoparticles (BiNPs) for antimicrobial treatments is scarce. Most of the current protocols for synthesizing...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210455/ https://www.ncbi.nlm.nih.gov/pubmed/32405464 http://dx.doi.org/10.1016/j.mex.2020.100894 |
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author | Vazquez-Munoz, Roberto Arellano-Jimenez, M. Josefina Lopez-Ribot, Jose L. |
author_facet | Vazquez-Munoz, Roberto Arellano-Jimenez, M. Josefina Lopez-Ribot, Jose L. |
author_sort | Vazquez-Munoz, Roberto |
collection | PubMed |
description | Bismuth is a water-insoluble non-toxic metallic element used in a wide array of pharmaceutical products, cosmetics, and catalysts, among others. Yet, the research regarding the use of bismuth nanoparticles (BiNPs) for antimicrobial treatments is scarce. Most of the current protocols for synthesizing BiNPs suitable for medical uses cannot be easily replicated in non-specialized laboratories. The objective of this work is to provide a fast, facile and economical method for synthesizing BiNPs. Bismuth nanoparticles were synthesized by a chemical reduction process, in less than 1 h, in a heated alkaline glycine solution; by the chelation and reduction of the bismuth (III) ions using dimercaptopropanol (BAL) and sodium borohydride respectively, and then coated and stabilized by polyvinylpyrrolidone (PVP). The resulting PVP-BiNPs were characterized by UV–Vis spectrophotometry and transmission electron microscopy (TEM). • We describe a simple, rapid and inexpensive method for the synthesis of bismuth nanoparticles. • This method allows synthesizing small nanoparticles with an aspect ratio close to one. • Bismuth nanoparticles have antimicrobial properties, this easy-to-replicate protocol may further the research on bismuth nanoparticles for biomedical applications. |
format | Online Article Text |
id | pubmed-7210455 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72104552020-05-13 Fast, facile synthesis method for BAL-mediated PVP-bismuth nanoparticles Vazquez-Munoz, Roberto Arellano-Jimenez, M. Josefina Lopez-Ribot, Jose L. MethodsX Materials Science Bismuth is a water-insoluble non-toxic metallic element used in a wide array of pharmaceutical products, cosmetics, and catalysts, among others. Yet, the research regarding the use of bismuth nanoparticles (BiNPs) for antimicrobial treatments is scarce. Most of the current protocols for synthesizing BiNPs suitable for medical uses cannot be easily replicated in non-specialized laboratories. The objective of this work is to provide a fast, facile and economical method for synthesizing BiNPs. Bismuth nanoparticles were synthesized by a chemical reduction process, in less than 1 h, in a heated alkaline glycine solution; by the chelation and reduction of the bismuth (III) ions using dimercaptopropanol (BAL) and sodium borohydride respectively, and then coated and stabilized by polyvinylpyrrolidone (PVP). The resulting PVP-BiNPs were characterized by UV–Vis spectrophotometry and transmission electron microscopy (TEM). • We describe a simple, rapid and inexpensive method for the synthesis of bismuth nanoparticles. • This method allows synthesizing small nanoparticles with an aspect ratio close to one. • Bismuth nanoparticles have antimicrobial properties, this easy-to-replicate protocol may further the research on bismuth nanoparticles for biomedical applications. Elsevier 2020-04-19 /pmc/articles/PMC7210455/ /pubmed/32405464 http://dx.doi.org/10.1016/j.mex.2020.100894 Text en © 2020 The Author(s). Published by Elsevier B.V. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Materials Science Vazquez-Munoz, Roberto Arellano-Jimenez, M. Josefina Lopez-Ribot, Jose L. Fast, facile synthesis method for BAL-mediated PVP-bismuth nanoparticles |
title | Fast, facile synthesis method for BAL-mediated PVP-bismuth nanoparticles |
title_full | Fast, facile synthesis method for BAL-mediated PVP-bismuth nanoparticles |
title_fullStr | Fast, facile synthesis method for BAL-mediated PVP-bismuth nanoparticles |
title_full_unstemmed | Fast, facile synthesis method for BAL-mediated PVP-bismuth nanoparticles |
title_short | Fast, facile synthesis method for BAL-mediated PVP-bismuth nanoparticles |
title_sort | fast, facile synthesis method for bal-mediated pvp-bismuth nanoparticles |
topic | Materials Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210455/ https://www.ncbi.nlm.nih.gov/pubmed/32405464 http://dx.doi.org/10.1016/j.mex.2020.100894 |
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