Elucidation of the Effects of a Current X-SCID Therapy on Intestinal Lymphoid Organogenesis Using an In Vivo Animal Model

BACKGROUND & AIMS: Organ-level research using an animal model lacking Il2rg, the gene responsible for X-linked severe combined immunodeficiency (X-SCID), is clinically unavailable and would be a powerful tool to gain deeper insights into the symptoms of patients with X-SCID. METHODS: We used an...

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Detalles Bibliográficos
Autores principales: Nochi, Tomonori, Suzuki, Shunichi, Ito, Shun, Morita, Shotaro, Furukawa, Mutsumi, Fuchimoto, Daiichiro, Sasahara, Yoji, Usami, Katsuki, Niimi, Kanae, Itano, Osamu, Kitago, Minoru, Matsuda, Sachiko, Matsuo, Ayumi, Suyama, Yoshihisa, Sakai, Yoshifumi, Wu, Guoyao, Bazer, Fuller W., Watanabe, Kouichi, Onishi, Akira, Aso, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210612/
https://www.ncbi.nlm.nih.gov/pubmed/32017983
http://dx.doi.org/10.1016/j.jcmgh.2020.01.011

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