Recurrent unintentional filtering blebs after vitrectomy: A case report

A lady who underwent lensectomy for microspherophakia and pars plana vitrectomy for retinal detachment in her left eye developed recurrent filtering blebs at the site of sclerotomies. Filtering blebs were managed by suturing the sclerotomies. Targeted gene sequencing identified a variant of ASPH gen...

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Detalles Bibliográficos
Autores principales: Shanmugam, P Mahesh, Sagar, Pradeep, Konana, Vinaya K, Simakurthy, Sriram, Ramanjulu, Rajesh, Sheemar, Abhishek, KC, Divyansh Mishra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210861/
https://www.ncbi.nlm.nih.gov/pubmed/32174599
http://dx.doi.org/10.4103/ijo.IJO_1249_19
Descripción
Sumario:A lady who underwent lensectomy for microspherophakia and pars plana vitrectomy for retinal detachment in her left eye developed recurrent filtering blebs at the site of sclerotomies. Filtering blebs were managed by suturing the sclerotomies. Targeted gene sequencing identified a variant of ASPH gene (p.Arg688Gln) which is not known to be associated with Traboulsi syndrome. But considering the paucity of cases with genetic analysis, it would be possible that p.Arg688Gln is a pathogenic variant. This is the first case report of Traboulsi syndrome due to an ASPH variant not reported earlier that can lead to recurrent filtering blebs.

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