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The interdependence of mammary-specific super-enhancers and their native promoters facilitates gene activation during pregnancy
Lineage-specific genetic programs rely on cell-restricted super-enhancers, which are platforms for high-density transcription factor occupation. It is not known whether super-enhancers synergize specifically with their native promoters or provide autonomous and independent regulatory platforms. Here...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210877/ https://www.ncbi.nlm.nih.gov/pubmed/32321991 http://dx.doi.org/10.1038/s12276-020-0425-x |