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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
Depression is a leading cause of worldwide disability but there remains considerable uncertainty regarding its neural and behavioural associations. Here, using non-overlapping Psychiatric Genomics Consortium (PGC) datasets as a reference, we estimate polygenic risk scores for depression (depression-...
Autores principales: | Shen, Xueyi, Howard, David M., Adams, Mark J., Hill, W. David, Clarke, Toni-Kim, Deary, Ian J., Whalley, Heather C., McIntosh, Andrew M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210889/ https://www.ncbi.nlm.nih.gov/pubmed/32385265 http://dx.doi.org/10.1038/s41467-020-16022-0 |
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