Cargando…
Flexibility of intrinsically disordered degrons in AUX/IAA proteins reinforces auxin co-receptor assemblies
Cullin RING-type E3 ubiquitin ligases SCF(TIR1/AFB1-5) and their AUX/IAA targets perceive the phytohormone auxin. The F-box protein TIR1 binds a surface-exposed degron in AUX/IAAs promoting their ubiquitylation and rapid auxin-regulated proteasomal degradation. Here, by adopting biochemical, structu...
Autores principales: | Niemeyer, Michael, Moreno Castillo, Elena, Ihling, Christian H., Iacobucci, Claudio, Wilde, Verona, Hellmuth, Antje, Hoehenwarter, Wolfgang, Samodelov, Sophia L., Zurbriggen, Matias D., Kastritis, Panagiotis L., Sinz, Andrea, Calderón Villalobos, Luz Irina A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210949/ https://www.ncbi.nlm.nih.gov/pubmed/32385295 http://dx.doi.org/10.1038/s41467-020-16147-2 |
Ejemplares similares
-
Author Correction: Flexibility of intrinsically disordered degrons in AUX/IAA proteins reinforces auxin co-receptor assemblies
por: Niemeyer, Michael, et al.
Publicado: (2021) -
Variation in auxin sensing guides AUX/IAA transcriptional repressor ubiquitylation and destruction
por: Winkler, Martin, et al.
Publicado: (2017) -
The mIAA7 degron improves auxin-mediated degradation in Caenorhabditis elegans
por: Sepers, Jorian J, et al.
Publicado: (2022) -
A combinatorial TIR1/AFB-Aux/IAA co-receptor system for differential sensing of auxin
por: Villalobos, Luz Irina A. Calderón, et al.
Publicado: (2012) -
Auxin Extraction and Purification Based on Recombinant Aux/IAA Proteins
por: Su, Yi, et al.
Publicado: (2017)