Cargando…
Comprehensive characterisation of pancreatic ductal adenocarcinoma with microsatellite instability: histology, molecular pathology and clinical implications
OBJECTIVE: Recently, tumours with microsatellite instability (MSI)/defective DNA mismatch repair (dMMR) have gained considerable interest due to the success of immunotherapy in this molecular setting. Here, we aim to clarify clinical-pathological and/or molecular features of this tumour subgroup thr...
Autores principales: | Luchini, Claudio, Brosens, Lodewijk A A, Wood, Laura D, Chatterjee, Deyali, Shin, Jae Il, Sciammarella, Concetta, Fiadone, Giulia, Malleo, Giuseppe, Salvia, Roberto, Kryklyva, Valentyna, Piredda, Maria L, Cheng, Liang, Lawlor, Rita T, Adsay, Volkan, Scarpa, Aldo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211065/ https://www.ncbi.nlm.nih.gov/pubmed/32350089 http://dx.doi.org/10.1136/gutjnl-2020-320726 |
Ejemplares similares
-
Epithelial-mesenchymal transition in undifferentiated carcinoma of the pancreas with and without osteoclast-like giant cells
por: Mattiolo, Paola, et al.
Publicado: (2020) -
Tumor Mutational Burden as a Potential Biomarker for Immunotherapy in Pancreatic Cancer: Systematic Review and Still-Open Questions
por: Lawlor, Rita T., et al.
Publicado: (2021) -
“Pure” hepatoid tumors of the pancreas harboring CTNNB1 somatic mutations: a new entity among solid pseudopapillary neoplasms
por: Mattiolo, Paola, et al.
Publicado: (2022) -
Immune landscape, evolution, hypoxia-mediated viral mimicry pathways and therapeutic potential in molecular subtypes of pancreatic neuroendocrine tumours
por: Young, Kate, et al.
Publicado: (2021) -
Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size
por: Hackeng, Wenzel M, et al.
Publicado: (2022)