Cargando…
Ginsenoside Rg1 ameliorates the cognitive deficits in D-galactose and AlCl(3)-induced aging mice by restoring FGF2-Akt and BDNF-TrkB signaling axis to inhibit apoptosis
Ginsenoside Rg1 is the main active ingredient of Panax ginseng with the activity of neuroprotective, antioxidant and strengthening the immune system. Therefore, we hypothesized that Rg1 may afford anti-aging effects although the mechanism remains to be elucidated. In this study, chemically induced a...
Autores principales: | Zhong, Si-Jia, Wang, Lin, Gu, Run-Ze, Zhang, Wen-Hao, Lan, Rongfeng, Qin, Xiao-Yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211162/ https://www.ncbi.nlm.nih.gov/pubmed/32410834 http://dx.doi.org/10.7150/ijms.43979 |
Ejemplares similares
-
The Role of BDNF-TrkB Signaling in the Pathogenesis of PTSD
por: Green, Christopher R., et al.
Publicado: (2013) -
Coeloglossum viride Var. Bracteatum Extract Attenuates MPTP-Induced Neurotoxicity in vivo by Restoring BDNF-TrkB and FGF2-Akt Signaling Axis and Inhibiting RIP1-Driven Inflammation
por: Lang, Xiu-Yuan, et al.
Publicado: (2022) -
The Functional Vision Restorative Effect of Crocin via the BDNF–TrkB Pathway: An In Vivo Study
por: Wu, Jia-Lain, et al.
Publicado: (2022) -
BDNF-induced TrkB activation down-regulates the K(+)–Cl(−) cotransporter KCC2 and impairs neuronal Cl(−) extrusion
por: Rivera, Claudio, et al.
Publicado: (2002) -
TrkB/BDNF signalling patterns the sympathetic nervous system
por: Kasemeier-Kulesa, Jennifer C., et al.
Publicado: (2015)