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Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19
The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreadin...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Author. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211669/ https://www.ncbi.nlm.nih.gov/pubmed/32422375 http://dx.doi.org/10.1016/j.ijid.2020.05.025 |
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author | Beldomenico, Pablo M. |
author_facet | Beldomenico, Pablo M. |
author_sort | Beldomenico, Pablo M. |
collection | PubMed |
description | The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreading events, in which new infections caused by a superspreader are more likely to be highly infectious. The mechanism suggested for this is related to viral loads. Exposure to high viral loads may result in high-intensity infection, which exposes new cases to high viral loads. This notion is supported by experimental veterinary research. |
format | Online Article Text |
id | pubmed-7211669 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Author. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72116692020-05-11 Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19 Beldomenico, Pablo M. Int J Infect Dis Perspective The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreading events, in which new infections caused by a superspreader are more likely to be highly infectious. The mechanism suggested for this is related to viral loads. Exposure to high viral loads may result in high-intensity infection, which exposes new cases to high viral loads. This notion is supported by experimental veterinary research. The Author. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020-07 2020-05-11 /pmc/articles/PMC7211669/ /pubmed/32422375 http://dx.doi.org/10.1016/j.ijid.2020.05.025 Text en © 2020 The Author Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Perspective Beldomenico, Pablo M. Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19 |
title | Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19 |
title_full | Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19 |
title_fullStr | Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19 |
title_full_unstemmed | Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19 |
title_short | Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19 |
title_sort | do superspreaders generate new superspreaders? a hypothesis to explain the propagation pattern of covid-19 |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211669/ https://www.ncbi.nlm.nih.gov/pubmed/32422375 http://dx.doi.org/10.1016/j.ijid.2020.05.025 |
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