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Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19

The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreadin...

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Detalles Bibliográficos
Autor principal: Beldomenico, Pablo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211669/
https://www.ncbi.nlm.nih.gov/pubmed/32422375
http://dx.doi.org/10.1016/j.ijid.2020.05.025
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author Beldomenico, Pablo M.
author_facet Beldomenico, Pablo M.
author_sort Beldomenico, Pablo M.
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description The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreading events, in which new infections caused by a superspreader are more likely to be highly infectious. The mechanism suggested for this is related to viral loads. Exposure to high viral loads may result in high-intensity infection, which exposes new cases to high viral loads. This notion is supported by experimental veterinary research.
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spelling pubmed-72116692020-05-11 Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19 Beldomenico, Pablo M. Int J Infect Dis Perspective The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreading events, in which new infections caused by a superspreader are more likely to be highly infectious. The mechanism suggested for this is related to viral loads. Exposure to high viral loads may result in high-intensity infection, which exposes new cases to high viral loads. This notion is supported by experimental veterinary research. The Author. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020-07 2020-05-11 /pmc/articles/PMC7211669/ /pubmed/32422375 http://dx.doi.org/10.1016/j.ijid.2020.05.025 Text en © 2020 The Author Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Perspective
Beldomenico, Pablo M.
Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19
title Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19
title_full Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19
title_fullStr Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19
title_full_unstemmed Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19
title_short Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19
title_sort do superspreaders generate new superspreaders? a hypothesis to explain the propagation pattern of covid-19
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211669/
https://www.ncbi.nlm.nih.gov/pubmed/32422375
http://dx.doi.org/10.1016/j.ijid.2020.05.025
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