Cargando…

The MiR-17-92 Gene Cluster is a Blood-Based Marker for Cancer Detection in Non-Small-Cell Lung Cancer

BACKGROUND: Lung cancer is one of the most malignant cancers threatening human health. The miR-17-92 gene cluster is a highly conserved oncogene cluster encoding 6 miRNAs: miR-17, miR-18a, miR-19a, miR-19b-1, miR-20a and miR-92a. This study explored whether these miRNAs can be used as diagnostic mar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Chenghao, Jia, Xiaoyu, Zhou, Jinbao, Sun, Qiangling, Ma, Zhongliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Southern Society for Clinical Investigation. Published by Elsevier Inc. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211762/ https://www.ncbi.nlm.nih.gov/pubmed/32466856 http://dx.doi.org/10.1016/j.amjms.2020.05.004

Ejemplares similares

Biology of MiR-17-92 Cluster and Its Progress in Lung Cancer
por: Zhang, Xinju, et al.
Publicado: (2018)

Insights into Regulation of the miR-17-92 Cluster of miRNAs in Cancer
por: Fuziwara, Cesar Seigi, et al.
Publicado: (2015)

miR-17–92 cluster: ups and downs in cancer and aging
por: Grillari, Johannes, et al.
Publicado: (2010)

miR-17 acts as a tumor suppressor by negatively regulating the miR-17-92 cluster
por: Sweat, Yan, et al.
Publicado: (2021)

Feud or Friend? The Role of the miR-17-92 Cluster in Tumorigenesis
por: Xiang, Jie, et al.
Publicado: (2010)

Evaluation of Serum miR-17-92 Cluster as Noninvasive Biomarkers for Bladder Cancer Diagnosis
por: Wang, Jingyao, et al.
Publicado: (2021)

miR-224-5p-enriched exosomes promote tumorigenesis by directly targeting androgen receptor in non-small cell lung cancer
por: Zhou, Jinbao, et al.
Publicado: (2021)

Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development
por: Zindy, Frederique, et al.
Publicado: (2014)

Roles of miR-17-92 Cluster in Cardiovascular Development and Common Diseases
por: Gu, Huanyu, et al.
Publicado: (2017)

miR-17-92 cluster in osteoarthritis: Regulatory roles and clinical utility
por: Pan, Xuefeng, et al.
Publicado: (2022)

Prognostic Value of the miR-17~92 Cluster in Chronic Lymphocytic Leukemia
por: Chocholska, Sylwia, et al.
Publicado: (2023)

MicroRNA Expression Profile Reveals miR-17-92 and miR-143-145 Cluster in Synchronous Colorectal Cancer
por: Meng, Wen-Jian, et al.
Publicado: (2015)

SRSF3 shapes the structure of miR‐17‐92 cluster RNA and promotes selective processing of miR‐17 and miR‐20a
por: Ratnadiwakara, Madara, et al.
Publicado: (2023)

Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells
por: Hu, Shien, et al.
Publicado: (2015)

The regulatory and predictive functions of miR-17 and miR-92 families on cisplatin resistance of non-small cell lung cancer
por: Zhao, Jian, et al.
Publicado: (2015)

Differential expression of the miR-17-92 cluster and miR-17 family in breast cancer according to tumor type; results from the Norwegian Women and Cancer (NOWAC) study
por: Moi, Line, et al.
Publicado: (2019)

The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer
por: Ottman, Richard, et al.
Publicado: (2016)

HNRNPA2B1 Affects the Prognosis of Esophageal Cancer by Regulating the miR-17-92 Cluster
por: Li, Kexin, et al.
Publicado: (2021)

miR-17-92 expression in differentiated T cells - implications for cancer immunotherapy
por: Sasaki, Kotaro, et al.
Publicado: (2010)

miR-17-92a-1 cluster host gene (MIR17HG) evaluation and response to neoadjuvant chemoradiotherapy in rectal cancer
por: Molinari, Chiara, et al.
Publicado: (2016)

The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors
por: Gruszka, Renata, et al.
Publicado: (2018)

Germline deletion of the miR-17-92 cluster causes growth and skeletal defects in humans
por: de Pontual, Loïc, et al.
Publicado: (2011)

Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma – reasons and consequences
por: Arabi, Leila, et al.
Publicado: (2014)

Expression, regulation and mechanism of action of the miR-17-92 cluster in tumor cells (Review)
por: Fang, Li-Li, et al.
Publicado: (2017)

Inhibition of miR-17~92 Cluster Ameliorates High Glucose-Induced Podocyte Damage
por: Fan, Xiaobao, et al.
Publicado: (2020)

TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis
por: Díez-Ricote, Laura, et al.
Publicado: (2022)

microRNA-17 Is the Most Up-Regulated Member of the miR-17-92 Cluster during Early Colon Cancer Evolution
por: Knudsen, Kirsten Nguyen, et al.
Publicado: (2015)

The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells
por: Cioffi, Michele, et al.
Publicado: (2015)

Functional polymorphisms in the promoter region of miR-17-92 cluster are associated with a decreased risk of colorectal cancer
por: Sun, Ruifen, et al.
Publicado: (2017)

The miR-17-92 cluster as a potential biomarker for the early diagnosis of gastric cancer: evidence and literature review
por: Li, Hong, et al.
Publicado: (2017)

Anti-microRNA screen uncovers miR-17 family within miR-17~92 cluster as the primary driver of kidney cyst growth
por: Yheskel, Matanel, et al.
Publicado: (2019)

The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25
por: Khuu, Cuong, et al.
Publicado: (2016)

Downregulated miR-18a and miR-92a synergistically suppress non-small cell lung cancer via targeting Sprouty 4
por: Zhang, Xinju, et al.
Publicado: (2022)

MicroRNA miR-92a-1 biogenesis and mRNA targeting is modulated by a tertiary contact within the miR-17∼92 microRNA cluster
por: Chaulk, Steven G., et al.
Publicado: (2014)

The Antileukemia Activity of Natural Product HQ17(3) Is Possibly Associated with Downregulation of miR-17-92 Cluster
por: Liao, Ya-Chun, et al.
Publicado: (2014)

The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma
por: Schwentner, Raphaela, et al.
Publicado: (2016)

Spatiotemporal plasticity of miRNAs functions: The miR-17-92 case
por: Bonaldi, Tiziana, et al.
Publicado: (2016)

MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours
por: Gits, C M M, et al.
Publicado: (2013)

Analysis of Transcriptional Regulation of the Human miR-17-92 Cluster; Evidence for Involvement of Pim-1
por: Thomas, Maren, et al.
Publicado: (2013)

The miR-17 ∼ 92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis
por: Philippe, Lucas, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ol3pla7fadk50jtcu9l2985ohf