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A Preclinical Investigation into the Effects of Aging on Dermal Hyaluronan Properties and Reconstitution Following Recombinant Human Hyaluronidase PH20 Administration

INTRODUCTION: There is currently no consensus in the literature concerning the impact of aging on the properties of hyaluronan (HA) in the subcutaneous (SC) space. Recombinant human hyaluronidase PH20 (rHuPH20) facilitates SC administration of injected therapeutics by depolymerizing SC HA, facilitat...

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Detalles Bibliográficos
Autores principales:	Connor, Robert J., Blouw, Barbara, Cowell, Jessica, Chen, Kelly, Zhao, Chunmei, Kang, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211778/ https://www.ncbi.nlm.nih.gov/pubmed/32361894 http://dx.doi.org/10.1007/s13555-020-00380-0

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