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COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients

INTRODUCTION: Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic are still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population. METHODS: Retrospective analysis of anonymized data including a...

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Detalles Bibliográficos
Autores principales: Härter, Georg, Spinner, Christoph D., Roider, Julia, Bickel, Markus, Krznaric, Ivanka, Grunwald, Stephan, Schabaz, Farhad, Gillor, Daniel, Postel, Nils, Mueller, Matthias C., Müller, Markus, Römer, Katja, Schewe, Knud, Hoffmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211976/
https://www.ncbi.nlm.nih.gov/pubmed/32394344
http://dx.doi.org/10.1007/s15010-020-01438-z
Descripción
Sumario:INTRODUCTION: Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic are still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population. METHODS: Retrospective analysis of anonymized data including age, gender, HIV-associated parameters, symptoms, and outcome. RESULTS: Three out of 32 patients with documented outcomes died (9%). 91% of the patients recovered and 76% have been classified as mild cases. All patients were on antiretroviral treatment, of them 22 on tenofovir-containing regimen and 4 on the protease inhibitor darunavir. CONCLUSIONS: This preliminary case series does not support excess morbidity and mortality among symptomatic COVID-19 PLWH and with viral suppression on ART. SARS-CoV-2 infections may occur during boosted darunavir-based and/or on tenofovir-containing ART.