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Single-cell O(2) exchange imaging shows that cytoplasmic diffusion is a dominant barrier to efficient gas transport in red blood cells
Disorders of oxygen transport are commonly attributed to inadequate carrying capacity (anemia) but may also relate to inefficient gas exchange by red blood cells (RBCs), a process that is poorly characterized yet assumed to be rapid. Without direct measurements of gas exchange at the single-cell lev...
Autores principales: | Richardson, Sarah L., Hulikova, Alzbeta, Proven, Melanie, Hipkiss, Ria, Akanni, Magbor, Roy, Noémi B. A., Swietach, Pawel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211990/ https://www.ncbi.nlm.nih.gov/pubmed/32321831 http://dx.doi.org/10.1073/pnas.1916641117 |
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