AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

Mitophagy is a key process regulating mitochondrial quality control. Several mechanisms have been proposed to regulate mitophagy, but these have mostly been studied using stably expressed non‐native proteins in immortalized cell lines. In skeletal muscle, mitophagy and its molecular mechanisms requi...

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Detalles Bibliográficos
Autores principales: Seabright, Alex P., Fine, Nicholas H. F., Barlow, Jonathan P., Lord, Samuel O., Musa, Ibrahim, Gray, Alexander, Bryant, Jack A., Banzhaf, Manuel, Lavery, Gareth G., Hardie, D. Grahame, Hodson, David J., Philp, Andrew, Lai, Yu‐Chiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212019/
https://www.ncbi.nlm.nih.gov/pubmed/32201986
http://dx.doi.org/10.1096/fj.201903051R

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