KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

The importance of germline-inherited posttranslational histone modifications on priming early mammalian development is just emerging(1–4). Histone H3 lysine 9 (H3K9) trimethylation is associated with heterochromatin and gene repression during cell-fate change(5), while histone H3 lysine 4 (H3K4) tri...

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Detalles Bibliográficos
Autores principales: Sankar, Aditya, Lerdrup, Mads, Manaf, Adeel, Johansen, Jens Vilstrup, Gonzalez, Javier Martin, Borup, Rehannah, Blanshard, Robert, Klungland, Arne, Hansen, Klaus, Andersen, Claus Yding, Dahl, John Arne, Helin, Kristian, Hoffmann, Eva R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212036/
https://www.ncbi.nlm.nih.gov/pubmed/32231309
http://dx.doi.org/10.1038/s41556-020-0494-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212036/
https://www.ncbi.nlm.nih.gov/pubmed/32231309
http://dx.doi.org/10.1038/s41556-020-0494-z

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