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Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma

INTRODUCTION: Alveolar macrophages (AMs) are critical in the development of lung adenocarcinoma driven by epidermal growth factor receptor (EGFR) mutations. Whether interstitial macrophages (IMs) are also involved in lung tumorigenesis is still unclear. Thus, the aim of this study is to evaluate the...

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Detalles Bibliográficos
Autores principales: Alikhanyan, Kristina, Chen, Yuanyuan, Kraut, Simone, Sotillo, Rocio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212197/
https://www.ncbi.nlm.nih.gov/pubmed/32125091
http://dx.doi.org/10.1002/iid3.293

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