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Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma
INTRODUCTION: Alveolar macrophages (AMs) are critical in the development of lung adenocarcinoma driven by epidermal growth factor receptor (EGFR) mutations. Whether interstitial macrophages (IMs) are also involved in lung tumorigenesis is still unclear. Thus, the aim of this study is to evaluate the...
Autores principales: | Alikhanyan, Kristina, Chen, Yuanyuan, Kraut, Simone, Sotillo, Rocio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212197/ https://www.ncbi.nlm.nih.gov/pubmed/32125091 http://dx.doi.org/10.1002/iid3.293 |
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