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Statins and the COVID-19 main protease: in silico evidence on direct interaction
INTRODUCTION: No proven drug and no immunisation are yet available for COVID-19 disease. The SARS-CoV-2 main protease (Mpro), a key coronavirus enzyme, which is a potential drug target, has been successfully crystallised. There is evidence suggesting that statins exert anti-viral activity and may bl...
Autores principales: | Reiner, Željko, Hatamipour, Mahdi, Banach, Maciej, Pirro, Matteo, Al-Rasadi, Khalid, Jamialahmadi, Tannaz, Radenkovic, Dina, Montecucco, Fabrizio, Sahebkar, Amirhossein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212226/ https://www.ncbi.nlm.nih.gov/pubmed/32399094 http://dx.doi.org/10.5114/aoms.2020.94655 |
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