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A WIZ/Cohesin/CTCF Complex Anchors DNA Loops to Define Gene Expression and Cell Identity
Chromosome structure is a key regulator of gene expression. CTCF and cohesin play critical roles in structuring chromosomes by mediating physical interactions between distant genomic sites. The resulting DNA loops often contain genes and their cis-regulatory elements. Despite the importance of DNA l...
Autores principales: | Justice, Megan, Carico, Zachary M., Stefan, Holden C., Dowen, Jill M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212317/ https://www.ncbi.nlm.nih.gov/pubmed/32294452 http://dx.doi.org/10.1016/j.celrep.2020.03.067 |
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