The Antagonism of 5-HT6 Receptor Attenuates Current-Induced Spikes and Improves Long-Term Potentiation via the Regulation of M-Currents in a Pilocarpine-Induced Epilepsy Model

Recent studies have documented that reduced M-current promotes epileptogenesis and attenuates synaptic remodeling. Neurite growth is closely related to the level of 5-HT6 receptor (5-HT6R) in the central nervous system. However, little research is available regarding the relation between 5-HT6R and...

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Detalles Bibliográficos
Autores principales: Zhu, Chaofeng, Lin, Rong, Liu, Changyun, Huang, Mingzhu, Lin, Feng, Zhang, Gan, Zhang, Yuying, Miao, Junjie, Lin, Wanhui, Huang, Huapin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212420/
https://www.ncbi.nlm.nih.gov/pubmed/32425770
http://dx.doi.org/10.3389/fphar.2020.00475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212420/
https://www.ncbi.nlm.nih.gov/pubmed/32425770
http://dx.doi.org/10.3389/fphar.2020.00475

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