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Cancer Cachexia Induces Preferential Skeletal Muscle Myosin Loss When Combined With Denervation

Patients with cancer cachexia (CCX) suffer from muscle wasting, which is often but not always accompanied by selective loss of myosin. Here we examined the effects of CCX on muscle mass and myosin heavy chain (MyHC) expression in denervated (DEN) muscles, especially focusing on the protein synthesis...

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Detalles Bibliográficos
Autores principales: Yamada, Takashi, Ashida, Yuki, Tatebayashi, Daisuke, Abe, Masami, Himori, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212425/
https://www.ncbi.nlm.nih.gov/pubmed/32425814
http://dx.doi.org/10.3389/fphys.2020.00445