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Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study

BACKGROUND: Positional weight matrix (PWM) is a de facto standard model to describe transcription factor (TF) DNA binding specificities. PWMs inferred from in vivo or in vitro data are stored in many databases and used in a plethora of biological applications. This calls for comprehensive benchmarki...

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Detalles Bibliográficos
Autores principales: Ambrosini, Giovanna, Vorontsov, Ilya, Penzar, Dmitry, Groux, Romain, Fornes, Oriol, Nikolaeva, Daria D., Ballester, Benoit, Grau, Jan, Grosse, Ivo, Makeev, Vsevolod, Kulakovskiy, Ivan, Bucher, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212583/
https://www.ncbi.nlm.nih.gov/pubmed/32393327
http://dx.doi.org/10.1186/s13059-020-01996-3